S&P 500 wavers, pressured by higher Treasury yields: Live updates

These are some of the stocks making notable moves in midday trading:

Click here for the full list.

— Alex Harring

Sales of Eli Lilly‘s obesity drug Zepbound are rising slower than many investors had hoped, which means the stock is continuing to languish. Once high-flying shares are down nearly 15% over the past three months.

But Morgan Stanley analyst Terence Flynn says Lilly continues to be one of the firm’s top picks with a $1,146 price target. That implies huge upside of nearly 50% from where shares closed on Monday.

Flynn cut fourth-quarter sales estimates for tirzepatide, the active ingredient in both Zepbound and diabetes drug Mounjaro, but he is standing firm on his 2025 projections. His revenue estimate for the year is 14% above consensus, while his earnings estimate is above the street by 26%.

“We believe both GLP-1 class growth and [Mounjaro-Zepbound] growth will accelerate more than consensus expects for multiple reasons…,” he said, citing improved supply, marketing spending, reduced impact from compounding pharmacies and improved insurance coverage as key factors.

—Christina Cheddar Berk

Mid-cap stocks outperformed Tuesday, after the latest economic data showing sticky inflation spurred a pivot away from large caps.

The Vanguard Mid-Cap ETF (VO) was down slightly, off by 0.1%, compared to the S&P 500’s 0.8% drop. In particular, mid-cap value stocks as represented by the Vanguard Mid-Cap Value ETF (VOE) gained 0.6%.

— Sarah Min

The U.S. services sector grew at a faster-than-expected pace in December, raising concern among investors about whether the Fed will be able to cut rates as much as Wall Street hopes, according to the Institute for Supply Management.

The ISM services sector PMI came in at 54.1. Economists polled by Dow Jones expected a print of 53.4. A key driver of that beat was the PMI’s price index — which soared 6.2 points to 64.4 — signaling there may be more inflation on the horizon.

— Fred Imbert

Stocks kicked off Tuesday’s trading session in the green, putting the S&P 500 and Nasdaq Composite on track to notch a three-day win streak.

The Dow Jones Industrial Average opened higher by about 179 points, or 0.4%. The S&P 500 added roughly 0.4%, while the tech-heavy Nasdaq jumped 0.3%.

— Pia Singh

The upswing for stocks in the past few trading days has reached a key technical area, according to BTIG strategist Jonathan Krinsky.

After slumping into year-end, the Invesco QQQ Trust (QQQ) could be on the verge of handing skeptics another loss, Krinsky said in a note to clients.

“QQQ is re-testing its broken trendline from the August lows, but it also appears to have broken the downtrend from recent highs. Betting against the Nasdaq has been futile, but if bears are going to make a stand it’s likely from around here,” Krinsky said.

The QQQ closed $524.54 per share on Monday. Its recent trading range stretches from a low of $434.77 in August and a high of $538.17 in December.

— Jesse Pound

These are the stocks making the biggest moves before the bell:

Read the full list here.

— Samantha Subin

Getty Images and Shutterstock announced a merger on Tuesday that brings together two digital image databases. Shares of both companies soared in premarket trading.

The combined company will keep the Getty name and be lead by Getty Images CEO Craig Peters. Shutterstock shareholders can choose to receive $28.85 per share as part of the deal. Other options include receiving Getty stock or a mix of cash and stock.

Shutterstock rose nearly 30%, while Getty Images rose more than 50%, though the stock is still below $5 per share.

The combined company will have an enterprise value of $3.7 billion, according to the announcement.

— Jesse Pound

Bank of America is an “overlooked” winner for 2025, according to UBS.

UBS analyst Erika Najarian upgraded shares of Bank of America to a buy rating from neutral. To accompany the move, she also lifted her 12-month price target to $53 from $43.

Shares of Bank of America have added 3% in 2025 and ended last year nearly 31% higher. Najarian’s updated price target implies that the stock could rise another 17% from its Monday close.

“In the post-election landscape of de-regulation and higher for longer, BAC has been largely left out of the conversation. We think the Street has not yet recalibrated EPS power from higher rates for longer,” the analyst wrote, calling its wide discount to peers JPMorgan Chase and Wells Fargo “unjustified.”

Notably, Najarian believes that the bank’s underlying assumptions to unlock net interest income outperformance are achievable. She also believes that Bank of America is an underrated beneficiary of deregulation.

Similarly, HSBC also upgraded Bank of America stock to a buy rating.

“The recent pullback provides an opportunity to add exposure to a market leader with an attractive earnings and profitability outlook at an attractive valuation,” wrote HSBC analyst Saul Martinez.

— Lisa Kailai Han

Japan’s Nikkei 225 led gains among Asian markets on Tuesday, gaining 1.97% and powered by a tech rally among semiconductor-related stocks.

Most other Asian markets also rose during the session, with the exception of Hong Kong.

The Hang Seng Index was 1.34% down in its final hour of trade, dragged by tech and health-care stocks.

Hong Kong-listed tech stocks are in the spotlight after the U.S. Defense Department added Chinese tech giant Tencent Holdings to a list of firms it calls “Chinese military companies.” Tencent‘s Hong Kong-listed shares are currently down over 7%.

— Lim Hui Jie

The recent increase in the notional value of short interest in Tesla stock, together with heightened volatility in the electrical vehicle maker’s shares, “underscores its growing market influence, surpassing both Nvidia and Apple in recent months,” according to S3 Partners, a researcher that specializes in tracking Wall Street short interest.

In a typical day, Tesla shares now move up or down in a range of 4.5% compared with its prior volatility of 3% to 4%, according to S3. Nvidia might typically move 3% to 4% each day although, unlike Tesla, its recent volatility has fallen, while Apple only moves 1% or so on an average day.

All three stocks are locked in a three-way race for the highest dollar value of shares sold short, S3 said. “NVDA has had the largest short interest notional position, but AAPL surpassed NVDA for two weeks in December. TSLA has been in third place since mid-year but has now surpassed AAPL,” according to the researcher.

— Scott Schnipper

These are the stocks moving the most in Monday’s after-hours trading:

• Inari Medical — Shares of medical device maker Inari Medical surged 22% after Reuters reported that the company was in advanced talks to be acquired by Stryker, citing people familiar with the matter. Sources said that a deal could be announced as early as this week.
• Ulta — The beauty retailer added nearly 2% after increasing its fourth-quarter outlook, citing a stronger-than-expected holiday season. The company also announced that CEO Dave Kimbell will retire after 11 years in the role, to be succeeded by current President and COO Kecia Steelman.

— Lisa Kailai Han

Stock futures traded higher on Monday night.

Dow futures added 48 points, or 0.1%, shortly after 6 p.m. ET. S&P 500 futures and Nasdaq 100 futures respectively gained 0.1% and 0.2%.

— Lisa Kailai Han